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Atpase may refer to:
A broad term for enzymes (ATP-driven ATPases) that catalyze ATP hydrolysis.
An ion pump that uses ATP to transport sodium and potassium across the plasma membrane.
An ATP-driven pump in the sarcoplasmic reticulum that transports Ca²⁺ for muscle relaxation.
An ATP-driven proton pump found in many intracellular organelles, acidifying them.
An ATP synthase that uses proton gradients to produce ATP (and can run in reverse as an ATPase).